Phospho-Raptor (S863) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-Raptor (S863) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Raptor Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S863 of human Raptor. Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coo |
| Immunogen | n/a |
| Other Names | [Regulatory-associated protein of mTOR; Raptor; p150 target of rapamycin (TOR)-scaffold protein; RPTOR; KIAA1303; RAPTOR] |
| Gene, Accession # | [RPTOR], Gene ID: 57521, NCBI: NP_065812.1, UniProt: Q8N122 |
| Catalog # | MBS9213802 |
| Price | $165, $370 |
| Order / More Info | Phospho-Raptor (S863) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Wang,Y., Circ. Res. 101 (6), 560-569 (2007) Fuchs,B.C., Am. J. Physiol., Cell Physiol. 293 (1), C55-C63 (2007) Olsen,J.V., Cell 127 (3), 635-648 (2006) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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