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Antigenic Specificity | CEMIP2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TMEM2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM2 |
Other Names | [cell surface hyaluronidase isoform a; Cell surface hyaluronidase; cell surface hyaluronidase; cell migration inducing hyaluronidase 2; Transmembrane protein 21 PublicationManual assertion based on opinion iniRef.1Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2.Scott D.A., Drury S., Sundstrom R.A., Bishop J., Swiderski R.E., Carmi R., Ramesh A., Elbedour K., Srikumari Srisailapathy C.R., Keats B.J., Sheffield V.C., Smith R.J.H.Gene 246:265-274(2000) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.] |
Gene, Accession # | [CEMIP2], Gene ID: 23670, NCBI: NP_037522, UniProt: Q9UHN6 |
Catalog # | MBS3206345 |
Price | $365 |
Order / More Info | CEMIP2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |