CEMIP2 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCEMIP2 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against TMEM2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM2
Other Names[cell surface hyaluronidase isoform a; Cell surface hyaluronidase; cell surface hyaluronidase; cell migration inducing hyaluronidase 2; Transmembrane protein 21 PublicationManual assertion based on opinion iniRef.1Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2.Scott D.A., Drury S., Sundstrom R.A., Bishop J., Swiderski R.E., Carmi R., Ramesh A., Elbedour K., Srikumari Srisailapathy C.R., Keats B.J., Sheffield V.C., Smith R.J.H.Gene 246:265-274(2000) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.]
Gene, Accession #[CEMIP2], Gene ID: 23670, NCBI: NP_037522, UniProt: Q9UHN6
Catalog #MBS3206345
Price$365
Order / More InfoCEMIP2 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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