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Antigenic Specificity | ATM (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5~34 amino acids from the N-terminal region of human ATM. Description: ATM is involved in signal transduction, cell cycle control and DNA repair, and may function as a tumor suppressor. It is necessary for activation of ABL1 and SAPK, and phosphorylates p53, NFKBIA, BRCA1, CTIP, NIBRIN (NBS1), TERF1, and RAD9. This protein has potential roles in vesicle and/or protein transport, T-cell development, gonad and neurological function. ATM is also part of the BRCA1-associated genome surveillance complex. ATM is induced by ionizing radiation. Defects in ATM are the cause of ataxia talangiectasia (AT), also known as Louis-Bar syndrome, a rare rece |
Immunogen | n/a |
Other Names | [Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM] |
Gene, Accession # | [ATM], Gene ID: 472, NCBI: NP_000042.3, UniProt: Q13315 |
Catalog # | MBS9217163 |
Price | $165, $370 |
Order / More Info | ATM (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Suzuki, A., et al., J. Biol. Chem. 278 (1):48-53 (2003). Kishi, S., et al., J. Biol. Chem. 276 (31):29282-29291 (2001). Schaffner, C., et al., Proc. Natl. Acad. Sci. U.S.A. 97 (6):2773-2778 (2000). Gatei, M., et al., Nat. Genet. 25 (1):115-119 (2000). Becker-Catania, S.G., et al., Mol. Genet. Metab. 70 (2):122-133 (2000). |