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Antigenic Specificity | CDC42 (Center), 106-134 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, chicken, monkey, mouse, porcine, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.46 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CDC42 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the Central region of human CDC42. CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates A |
Immunogen | n/a |
Other Names | [Cell division control protein 42 homolog; G25K GTP-binding protein; CDC42] |
Gene, Accession # | [CDC42], Gene ID: 998, NCBI: NP_001034891.1, UniProt: P60953 |
Catalog # | MBS9202753 |
Price | $165, $370 |
Order / More Info | CDC42 (Center), 106-134 Antibody from MYBIOSOURCE INC. |
Product Specific References | Landry,M.C., et.al., Mol. Biol. Cell 20 (18), 4091-4106 (2009) |