CENTG1 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCENTG1 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, guinea pig, horse, human, mouse, rabbit, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against CENTG1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: CENTG1 is a GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent traffickin
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human CENTG1
Other Names[arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform PIKE-A; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; Centaurin-gamma-1; Cnt-g1; GTP-binding and GTPase-activating protein 2; GGAP2; Phosphatidylinositol 3-kinase enhancer; PIKE]
Gene, Accession #[AGAP2], Gene ID: 116986, NCBI: NP_055585, UniProt: Q99490
Catalog #MBS3210747
Price$335
Order / More InfoCENTG1 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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