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Antigenic Specificity | CENTG1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CENTG1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: CENTG1 is a GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent traffickin |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CENTG1 |
Other Names | [arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform PIKE-A; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; Centaurin-gamma-1; Cnt-g1; GTP-binding and GTPase-activating protein 2; GGAP2; Phosphatidylinositol 3-kinase enhancer; PIKE] |
Gene, Accession # | [AGAP2], Gene ID: 116986, NCBI: NP_055585, UniProt: Q99490 |
Catalog # | MBS3210747 |
Price | $335 |
Order / More Info | CENTG1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |