Mouse CD40 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD40
Clone[2/23]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatbiotin conjugate
Size0.1 mg, 0.3 mg
ConcentrationAntibody concentration: 0.1 mg/ml
ApplicationsImmunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionSpecificity: CD40 (gp39 receptor) (Mouse CD40). anti-mouse monoclonal antibody reacts with CD40 which is expressed on B-lymphocytes and on a subset of both CD4+ and CD8+ T cells in the adult (but not neonatal) spleen1. The level of CD40 on B cells is enhanced following activation buy LPS1. The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal center formation, and generating B cell memory2. Stimulating cells with immobilized 3/23 mAb increases expression of CD86 (B7.2) on B cells1,3. Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3. Costimulation with 3/23 mAb and IL-4 rescues
Immunogenn/a
Other Names[CD40, Biotin (Clone 3/23) (rat IgG2a); Biotin Mouse CD40], [CD40; CD40; p50; Bp50; CDW40; TNFRSF5; TNFRSF5]
Gene, Accession #[CD40], Gene ID: 958, NCBI: NP_690593.1, UniProt: P25942
Catalog #MBS520120
Price$200, $370
Order / More InfoMouse CD40 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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