Cyclin D1 (G1-Cyclin & Mantle Cell Marker) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Cyclin D1 (G1-Cyclin & Mantle Cell Marker) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Cyclin D1 (G1-Cyclin & Mantle Cell Marker) |
| Clone | [SPM587] |
| Host Species | Mouse |
| Reactive Species | human, monkey, mouse, rat. |
| Isotype | IgG2a, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1. |
| Immunogen | Immunogen: Human recombinant full length cyclin D1 protein |
| Other Names | [B cell CLL/lymphoma 1, B cell leukemia 1, B-cell lymphoma 1 protein, BCL-1 oncogene, CCND1 protein, CCND1/FSTL3 fusion gene, CCND1/IGHG1 fusion gene CCND1/IGLC1 fusion gene, CCND1/PTH fusion gene, cD1, Cyl 1, G1/S-specific cyclin-D1, Parathyroid adenomatosis 1, PRAD1 oncogene], [CCND1; CCND1; BCL1; PRAD1; U21B31; D11S287E; BCL1; PRAD1; BCL-1] |
| Gene, Accession # | [CCND1], Gene ID: 595, NCBI: NP_444284.1, UniProt: P24385 |
| Catalog # | MBS438067 |
| Price | $190, $340, $340 |
| Order / More Info | Cyclin D1 (G1-Cyclin & Mantle Cell Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lukas J, et. al. Oncogene, 1994, 9(3):707-18. Gillett C, et. al. Cancer Research, 1994, 54(7):1812-7. Bartkova J, et. al. Journal of Pathology, 1994, 172(3):237-45 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies