Human Dkk-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Dkk-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg, 0.2 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /beta-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/betacatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/betacatenin signaling cascade. It has been suggested that by inhibiting Wnt/beta-catenin signaling, which is essential for posteri
ImmunogenAntibody Generation: Purified from sera of rabbits immunized with highly pure recombinant human DKK1 produced in E Coli. Antigen: Recombinant Human Dkk-1
Other Names[Dickkopf-related protein-1; Dickkopf-1; SK], [DKK1; DKK1; SK; DKK-1; Dickkopf-1; Dkk-1; hDkk-1]
Gene, Accession #[Dkk-1], Gene ID: 22943, NCBI: NP_036374.1, UniProt: O94907
Catalog #MBS692265
Price$280, $390
Order / More InfoHuman Dkk-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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