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Antigenic Specificity | STAM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STAM2 antibody detects endogenous levels of total STAM2. Function: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).Subunit Structure: Component of the ESCRT-0 complex composed of STAM or STAM2 and HGS. Part of |
Immunogen | Immunogen: A synthesized peptide derived from human STAM2 Subcellular Location: Cytoplasm. Early endosome membrane. Tissue Specificity: Ubiquitously expressed. Predicted Cross Reactivity: Pig, Bovine, Sheep, Dog, Chicken Similarity: Pig (89%), Bovine (89%), Sheep (89%), Dog (89%), Chicken (89%) |
Other Names | [DKFZp564C047; Hbp; Hrs-binding protein; HSE1 homolog; Signal transducing adapter molecule 2; Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; Signal transducing adaptor molecule 2A; Signal transducing adaptor molecule 2B; Signal transducing adaptor molecule; STAM like protein containing SH3 and ITAM domains 2; STAM-2; Stam2; STAM2_HUMAN; STAM2A; STAM2B] |
Gene, Accession # | [STAM2], Gene ID: 10254, NCBI: NP_005834.4, UniProt: O75886 |
Catalog # | MBS9602246 |
Price | $240, $280 |
Order / More Info | STAM2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |