STAM2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySTAM2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: STAM2 antibody detects endogenous levels of total STAM2. Function: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).Subunit Structure: Component of the ESCRT-0 complex composed of STAM or STAM2 and HGS. Part of
ImmunogenImmunogen: A synthesized peptide derived from human STAM2 Subcellular Location: Cytoplasm. Early endosome membrane. Tissue Specificity: Ubiquitously expressed. Predicted Cross Reactivity: Pig, Bovine, Sheep, Dog, Chicken Similarity: Pig (89%), Bovine (89%), Sheep (89%), Dog (89%), Chicken (89%)
Other Names[DKFZp564C047; Hbp; Hrs-binding protein; HSE1 homolog; Signal transducing adapter molecule 2; Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; Signal transducing adaptor molecule 2A; Signal transducing adaptor molecule 2B; Signal transducing adaptor molecule; STAM like protein containing SH3 and ITAM domains 2; STAM-2; Stam2; STAM2_HUMAN; STAM2A; STAM2B]
Gene, Accession #[STAM2], Gene ID: 10254, NCBI: NP_005834.4, UniProt: O75886
Catalog #MBS9602246
Price$240, $280
Order / More InfoSTAM2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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