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Antigenic Specificity | BMI1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BMI1 antibody detects endogenous levels of total BMI1. Description: The polycomb group (PcG) of proteins contributes to the maintenance of cell identity, stem cell self-renewal, cell cycle regulation, and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death, and cell-cycle arrest (1-4). PcG proteins exist in two complexes that cooperate to maintain long-term gene silencing through epigenetic chromatin modifications. The first complex, EED-EZH2, is recruited to genes by DNA-binding transcription factors and methylates histone H3 on Lys27. This histone methyl-transferase activity requires the Ezh2, Eed, and Suz12 subunits of the complex (5). Histone H3 methylation at Lys27 fac |
Immunogen | Immunogen: A synthesized peptide derived from human BMI1 Subcellular Location: Nucleus. Cytoplasm. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Chicken Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Chicken (90%) |
Other Names | [B lymphoma Mo MLV insertion region (mouse); B lymphoma Mo MLV insertion region 1 homolog; Bmi 1; BMI1; BMI1 polycomb ring finger oncogene; BMI1_HUMAN; Flvi 2/bmi 1; FLVI2/BMI1; MGC12685; Murine leukemia viral (bmi 1) oncogene homolog; Oncogene BMI 1; PCGF 4; PCGF4; Polycomb complex protein BMI 1; Polycomb complex protein BMI-1; Polycomb group protein Bmi1; Polycomb group ring finger 4; Polycomb group RING finger protein 4; RING finger protein 51; RNF 51; RNF51] |
Gene, Accession # | [BMI1], Gene ID: 100532731, NCBI: NP_001190991.1, UniProt: P35226 |
Catalog # | MBS9606685 |
Price | $240, $280 |
Order / More Info | BMI1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |