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Antigenic Specificity | RCHY1/PIRH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human RCHY1/PIRH2. Mediates E3-dependent ubiquitination and proteasomal degradation oftarget proteins, including p53/TP53, P73, HDAC1 and CDKN1B.Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. |
Immunogen | Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 59 and 261 (Q96PM5) of Pirh2. Percent identity by BLAST analysis: Human (100%); Rat (94%); Mouse (93%). Conjugation: Unconjugated |
Other Names | [Mouse [clone 1H10] (IgG1) to Human RCHY1/PIRH2; RCHY1; ARNIP; CHIMP; HARNIP; HPirh2; PIRH2E; PIRH2; PIRH2F; PRO1996; RING finger protein 199; Zinc finger protein 363; ZNF363; p53-induced RING-H2 protein; RNF199] |
Gene, Accession # | [RCHY1/PIRH2], Gene ID: 25898, NCBI: NP_056251.2, UniProt: Q96PM5 |
Catalog # | MBS2401665 |
Price | $530 |
Order / More Info | RCHY1/PIRH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |