CD45/LCA (Leucocyte Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD45/LCA (Leucocyte Marker)
Clone[Bra55]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (Formalin-Fixed)
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DescriptionSpecificity: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of
ImmunogenImmunogen: Recombinant full-length human PTPRC protein Positive Control: Ramos, U-698, or GA-10 Cells. Tonsil
Other Names[B220; CD45R; GP180; Leukocyte common antigen (LCA); Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC); Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein]
Gene, Accession #[CD45/LCA], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575
Catalog #MBS4380669
Price$190, $340, $340
Order / More InfoCD45/LCA (Leucocyte Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesChorvath B, et. al. Neoplasma, 1987, 34(6):685-92.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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