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Antigenic Specificity | Bim |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes BIM protein. It cross reacts to human, rat and mouse. The other species are not tested. Bim (bcl-2-interacting mediator of cell death, BCL-2-related Ovarian Death Gene) is a proapoptotic member of the Bcl-2 family that shares the homology domain3 (BH3) with this family. Bim exists in three isoforms: BimEL, BimL, and BimS. As the BCL-2 family members reside upstream of irreversible cellular damage and focus much of their efforts at the level of mitochondria, they play a pivotal role in deciding whether a cell will live or die. In healthy cells, BIM molecules are localized to the microtubule-associated dynein motor complex through association with the LC8 dynein light chain. Following a death signal, LC8 and BIM disso |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [Bim] |
Catalog # | MBS460210 |
Price | $285 |
Order / More Info | Bim Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Adams JM, Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 1998; 281 (5381):1322-1326. |