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Antigenic Specificity | NANOG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Expression of NANOG is required for the maintenance of pluripotency in epiblast and embryonic stem (ES) cells as well as for the ability to maintain ES self-renewal independently of LIF/Stat3. The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated usin |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 19 amino acid peptide near the center of human NANOG. |
Other Names | [NANOG homeobox] |
Gene, Accession # | [NANOG], Gene ID: 79923, NCBI: EAW88651 |
Catalog # | MBS9414559 |
Price | $320 |
Order / More Info | NANOG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |