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Antigenic Specificity | COL4A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cereb |
Immunogen | Immunogen: A synthetic peptide of human COL4A1 |
Other Names | [BSVD; RATOR] |
Gene, Accession # | [COL4A1], Gene ID: 1282, NCBI: P02462.3, UniProt: P02462 |
Catalog # | MBS9131103 |
Price | $200, $275, $430 |
Order / More Info | COL4A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |