ERN2 (C-term), 781-810 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ERN2 (C-term), 781-810 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-810 amino acids from the C-terminal region of human ERN2. ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells. |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase/endoribonuclease IRE2; Endoplasmic reticulum-to-nucleus signaling 2; Inositol-requiring protein 2; hIRE2p; Ire1-beta; IRE1b; Serine/threonine-protein kinase; Endoribonuclease; 3126-; ERN2 HGNC:16942)] |
| Gene, Accession # | [ERN2], Gene ID: 10595, NCBI: NP_150296.3, UniProt: Q76MJ5 |
| Catalog # | MBS9208277 |
| Price | $165, $370 |
| Order / More Info | ERN2 (C-term), 781-810 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Iwawaki, T., et al., Nat. Cell Biol. 3(2):158-164 (2001). Wang, X.Z., et al., EMBO J. 17(19):5708-5717 (1998). |
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MYBIOSOURCE INC.
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