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Antigenic Specificity | PP2AA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PP2AA protein. PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). It can dephosphorylate SV40 large T antigen and p53/TP53 and activates RAF1 by dephosphorylating it at 'Ser-259'. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PP2AA protein |
Other Names | [Rabbit PP2AA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C] |
Gene, Accession # | [PP2AA], Gene ID: 5515, NCBI: NP_002706.1, UniProt: P67775 |
Catalog # | MBS9710521 |
Price | $130, $220, $325 |
Order / More Info | PP2AA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |