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Antigenic Specificity | Chicken MHC Class I |
Clone | [F21-2] |
Host Species | Mouse |
Reactive Species | chicken |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry; Immunoprecipitation; Western Blot; Immunoaffinity Chromatography |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: A monomorphic epitope on avian MHC Class I molecules (Mr ~ 68 kDa). Like their mammalian counterparts, avian MHC Class I molecules (also known as B-F antigens) consist of a highly polymorphic alpha-chain (Mr ~ 44 kDa) non-covalently bound to the invariant beta 2-microglobulin subunit (Mr ~ 12 kDa). MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.1-3 MAb F21-2 also reacts with turkey MHC Class I.4. |
Immunogen | n/a |
Other Names | [Mouse Chicken MHC Class I - Purified, Unlabeled; Mouse Chicken MHC Class I], [gamr-UA-c24] |
Gene, Accession # | UniProt: O98279 |
Catalog # | MBS673929 |
Price | $305 |
Order / More Info | Chicken MHC Class I Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Salomonsen, J., K. Skjodt, M. Krone and M. Simonsen. 1987. Immunogenetics 25:373-382.2. L.B. Moller, J. Kaufman, S. Verland, J. Salomonsen, D. Avila, J.D. Lambris and K. Skjodt. 1991. Immunogenetics 34:110-120.3. Dunon, D., J. Salomonsen, K. Skjodt, J. Kaufman, and B.A. Imhof. 1990. Dev. Immunol. 1:127-135.5. Salomonsen, J. Personal communication. |