Phospho-GRB10 (Ser431) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-GRB10 (Ser431) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | humanpredicted: porcine, horse, sheep, rabbit, dog, chicken, Xenopus |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-GRB10 (Ser431) Antibody detects endogenous levels of GRB10 only when phosphorylated at Ser431. Description: Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to |
| Immunogen | Immunogen: A synthesized peptide derived from human GRB10 around the phosphorylation site of Ser431. Tissue Specificity: Widely expressed in fetal and adult tissues, including fetal and postnatal liver, lung, kidney, skeletal muscle, heart, spleen, skin and brain. |
| Other Names | [grb 10; GRB IR; grb-10; GRB10 adapter protein; GRB10 adaptor protein; GRB10; GRB10_HUMAN; GRBIR; Growth factor receptor bound protein 10; Growth factor receptor-bound protein 10; Insulin receptor binding protein; Insulin receptor binding protein GRB IR; Insulin receptor-binding protein Grb-IR; IRBP; KIAA0207; Maternally expressed gene 1; MEG1; RSS] |
| Gene, Accession # | [GRB10], Gene ID: 2887, NCBI: NP_001001549.1, UniProt: Q13322 |
| Catalog # | MBS9610732 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-GRB10 (Ser431) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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