POLR3E Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | POLR3E |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I |
| Immunogen | Immunogen: Recombinant human DNA-directed RNA polymerase III subunit RPC5 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-107950 / sc-107951 |
| Other Names | [DNA-directed RNA polymerase III subunit RPC5; RNA polymerase III subunit C5; POLR3E; KIAA1452; DNA-directed RNA polymerase III 80 kDa polypeptide], [POLR3E; POLR3E; SIN; RPC5; KIAA1452; RNA polymerase III subunit C5] |
| Gene, Accession # | [POLR3E], Gene ID: 55718, NCBI: NP_001244962.1, UniProt: Q9NVU0 |
| Catalog # | MBS1491829 |
| Price | $160, $235 |
| Order / More Info | POLR3E Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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