Lamin A/C Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Lamin A/C |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human Lamin A/C. Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6). |
| Immunogen | Immunogen: A fusion protein of human Lamin A/C |
| Other Names | [LMNA; LMNA; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; HGPS; IDC; LD P1; LFP; LGMD1B; LMN1; LMNC; PRO1;], [LMNA; LMNA; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B; LMN1] |
| Gene, Accession # | Gene ID: 4000, NCBI: NP_001244303.1, UniProt: P02545 |
| Catalog # | MBS125295 |
| Price | $275, $430 |
| Order / More Info | Lamin A/C Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Gruenbaum, Y. et al. (2000) J Struct Biol 129, 313-23. 2. Yabuki, M. et al. (1999) Physiol Chem Phys Med NMR 31, 77-84. 3. Goldberg, M. et al. (1999) Crit Rev Eukaryot Gene Expr 9, 285-93. 4. Orth, K. et al. (1996) J Biol Chem 271, 16443-6. 5. Oberhammer, F.A. et al. (1994) J Cell Biol 126, 827-37. 6. Rao, L. et al. (1996) J Cell Biol 135, 1441-55. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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