JNK1 (Thr183/Tyr185) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | JNK1 (Thr183/Tyr185) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat; predicted reactivity: human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 157-189 amino acids from human. Description: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcrip |
| Immunogen | n/a |
| Other Names | [Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; 2.7.11.24; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK8; JNK1; PRKM8; SAPK1; SAPK1C] |
| Gene, Accession # | [MAPK8], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
| Catalog # | MBS9217298 |
| Price | $165, $370 |
| Order / More Info | JNK1 (Thr183/Tyr185) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Derijard B.,et al.Cell 76:1025-1037 (1994). Gupta S.,et al.EMBO J. 15:2760-2770 (1996). Lin L.,et al.Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases. Deloukas P.,et al.Nature 429:375-381 (2004). Goshima N.,et al.Nat. Methods 5:1011-1017 (2008). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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