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Antigenic Specificity | FAM134B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FAM134B Antibody detects endogenous levels of FAM134B. Description: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).Subunit Structure: Interacts with ATG8 family modifier proteins MAP1LC3A, MAP1LC3B, GABARAP, GABARAPL1 and GABARAPL2.Similarity: The LIR motif interacts with ATG8 family proteins and is necessary to tar |
Immunogen | Immunogen: A synthesized peptide derived from human FAM134B. Tissue Specificity: Overexpressed in esophageal squamous cell carcinoma (PubMed:17487424). |
Other Names | [F134B_HUMAN; FAM134B; family with sequence similarity 134 member B; HSAN2B; JK 1; JK1; Protein FAM134B] |
Gene, Accession # | [FAM134B], Gene ID: 54463, NCBI: NP_001030022.1, UniProt: Q9H6L5 |
Catalog # | MBS9611748 |
Price | $240, $280 |
Order / More Info | FAM134B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |