FAM134B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAM134B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: FAM134B Antibody detects endogenous levels of FAM134B. Description: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).Subunit Structure: Interacts with ATG8 family modifier proteins MAP1LC3A, MAP1LC3B, GABARAP, GABARAPL1 and GABARAPL2.Similarity: The LIR motif interacts with ATG8 family proteins and is necessary to tar
ImmunogenImmunogen: A synthesized peptide derived from human FAM134B. Tissue Specificity: Overexpressed in esophageal squamous cell carcinoma (PubMed:17487424).
Other Names[F134B_HUMAN; FAM134B; family with sequence similarity 134 member B; HSAN2B; JK 1; JK1; Protein FAM134B]
Gene, Accession #[FAM134B], Gene ID: 54463, NCBI: NP_001030022.1, UniProt: Q9H6L5
Catalog #MBS9611748
Price$240, $280
Order / More InfoFAM134B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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