AKT1 (Thr308) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AKT1 (Thr308) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human. predicted cross reactivity with mouse, rat, bovine and Xenopus samples. |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polyclonal Antibody to detect AKT1 in human, mouse, rat, bovine and xenopus samples. Background: The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. They have a pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-? tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Phosphorylation of both residues is importan |
| Immunogen | Immunogen: This AKT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-309 amino acids from human AKT1. Positive Control: Western blot: 293 cell line lysates and mouse liver tissue lysates, IHC: human breast carcinoma tissue, FACS: MDA-MB435 cells. |
| Other Names | [PKB; RAC; Protein kinase B; Protein kinase B alpha; Short PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha], [AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha] |
| Gene, Accession # | [AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
| Catalog # | MBS841230 |
| Price | $320 |
| Order / More Info | AKT1 (Thr308) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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