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Antigenic Specificity | Dectin-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dectin-2 Polyclonal Antibody detects endogenous levels of Dectin-2 protein. The protein encoded by CLEC6A (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for CLEC6A. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Dectin-2 |
Other Names | [Rabbit Dectin-2; CLEC6A; CLECSF10; C-type lectin domain family 6 member A; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2; DC-associated C-type lectin 2; Dectin-2] |
Gene, Accession # | [DECTIN2], Gene ID: 93978, NCBI: NP_001007034.1, UniProt: Q6EIG7 |
Catalog # | MBS9707990 |
Price | $130, $220, $325 |
Order / More Info | Dectin-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |