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Antigenic Specificity | Synaptotagmin-3 |
Clone | [S278-19] |
Host Species | Mouse |
Reactive Species | rat, mouse, human |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~75kDa. Does not cross-react with other Synaptotagmins. Scientific Background: Synaptotagmins constitute a family of membrane- trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2 ) sensors in the process of vesicular trafficking and exocytosis. |
Immunogen | n/a |
Other Names | [SYT-3; SYT3; Synaptotagmin 3; Synaptotagmin III; SytIII; Syt III; Synaptotagmin3; SynaptotagminIII], [Syt3; Syt3; sytIII; AI385753; SytIII] |
Gene, Accession # | Gene ID: 20981, NCBI: NP_001107588.1, UniProt: O35681 |
Catalog # | MBS800218 |
Price | $435 |
Order / More Info | Synaptotagmin-3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Schengrund C.L., et al. (2002) J Biol Chem. 277: 32815. 2. Reichardt L.F., et al. (1981) J Cell Biol. 91:257. 3. Brown H., et al. (2000) Diabetes. 49: 383-391. |