ADAMTS13 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ADAMTS13 |
| Clone | [9H42] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human ADAMTS13. Does not crossreact with recombinant human ADAMTS1, ADAMTS4, ADAMTS5 or ADAMTS-L1.2. ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin motifs 13) is a secreted multi-domain zinc protease primarily produced by the liver. In the circulation, it is responsible for cleaving von Willebrand factor (vWF) between Tyr842 and Met843. Defects in ADAMTS13 activity result in the generation of ultra large vWF, leading to thrombotic thrombocytopenic purpura (TTP). The amino acid sequence of human ADAMTS13 in the region of aa34-688 is 76% identical to that of mouse/rat. |
| Immunogen | Immunogen: Recombinant protein corresponding to human ADAMTS13, isoform-1 (aa34-688 predicted), expressed in CHO cells (Q76LX8) Species Sequence Homology: mouse and rat, 76% |
| Other Names | ADAMTS13 (A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13) |
| Gene, Accession # | Gene ID: 11093, NCBI: NP_620596.2, UniProt: Q6QNA4 |
| Catalog # | MBS607328 |
| Price | $680 |
| Order / More Info | ADAMTS13 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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