Cytokeratin 10 (Suprabasal Epithelial Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cytokeratin 10 (Suprabasal Epithelial Marker) |
| Clone | [KRT10/1948R] |
| Host Species | Rabbit |
| Reactive Species | human, dog, Cat. |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiat |
| Immunogen | Immunogen: Recombinant full-length of human KRT10 protein Cellular Localization: Cytoplasmic |
| Other Names | [BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10] |
| Gene, Accession # | [KRT10], Gene ID: 3858, NCBI: NP_000412.3, UniProt: P13645 |
| Catalog # | MBS4380072 |
| Price | $190, $340, $340 |
| Order / More Info | Cytokeratin 10 (Suprabasal Epithelial Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ivanyi D, et. al. Differentiation, 1989, 42(2):124-9. Ivanyi D, et. al. Journal of Pathology, 1989, 159:7-12. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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