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Antigenic Specificity | Hsp70 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation (PubMed: |
Immunogen | Immunogen: A synthesized peptide derived from human Hsp70. Subcellular Localization: Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
Other Names | [Heat shock 70 kDa protein 1A; Heat shock 70 kDa protein 1; HSP70-1; HSP70.1; HSPA1A; HSPA1; HSX70], [HSPA1A] |
Gene, Accession # | [Hsp70], Gene ID: 3303, NCBI: NP_005336.3, UniProt: P0DMV8 |
Catalog # | MBS179497 |
Price | $160, $340, $340 |
Order / More Info | Hsp70 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |