Hsp70 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHsp70
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionIn cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation (PubMed:
ImmunogenImmunogen: A synthesized peptide derived from human Hsp70. Subcellular Localization: Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Other Names[Heat shock 70 kDa protein 1A; Heat shock 70 kDa protein 1; HSP70-1; HSP70.1; HSPA1A; HSPA1; HSX70], [HSPA1A]
Gene, Accession #[Hsp70], Gene ID: 3303, NCBI: NP_005336.3, UniProt: P0DMV8
Catalog #MBS179497
Price$160, $340, $340
Order / More InfoHsp70 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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