Edit |   |
---|---|
Antigenic Specificity | CaMKII alpha |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed: 23805378). Activates FOXO3 transcriptional activity (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human CaMKII alpha. Subcellular Localization: Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse. Postsynaptic lipid rafts. |
Other Names | [Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; 2.7.11.17; CAMK2A; CAMKA; KIAA0968], [CAMK2A; CAMK2A; CAMKA; MRD53; CAMKA; KIAA0968; CaM kinase II subunit alpha; CaMK-II subunit alpha] |
Gene, Accession # | [CAMK2A], Gene ID: 815, NCBI: NP_741960.1, UniProt: Q9UQM7 |
Catalog # | MBS179946 |
Price | $160, $340, $340 |
Order / More Info | CaMKII alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |