ARH (LDLRAP1) (N-term), 11-42 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityARH (LDLRAP1) (N-term), 11-42
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis ARH (LDLRAP1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-42 amino acids from the N-terminal region of human ARH (LDLRAP1). LDLRAP1 is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. This adapter protein is required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. This protein may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by sta
Immunogenn/a
Other Names[Low density lipoprotein receptor adapter protein 1; Autosomal recessive hypercholesterolemia protein; LDLRAP1; ARH]
Gene, Accession #[LDLRAP1], Gene ID: 26119, NCBI: NP_056442.2, UniProt: Q5SW96
Catalog #MBS9206647
Price$165, $370
Order / More InfoARH (LDLRAP1) (N-term), 11-42 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMaurer,M.E., J. Cell. Sci. 119 (PT 20), 4235-4246 (2006) Keyel,P.A., Mol. Biol. Cell 17 (10), 4300-4317 (2006)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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