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Antigenic Specificity | Human ITGB2 / MAC-1 / CD18 |
Clone | [MEM-48] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Functional Assay |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Leukocytes of a patient suffering from a LGL-type leukemia. Recognizes an epitope involving residues 534-546 incysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin). CD18 is a 90-95 kDa type I transmembrane protein expressed on al leukocytes. Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor |
Immunogen | Immunogen: ITCB2/CD18 antibody was raised against Human. Immunogen Species: ITCB2/CD18 antibody was raised against cells. |
Other Names | [ITGB2 / MAC-1 / CD18 (clone MEM-48) IHC-plus; ITGB2; CD18 antigen; CD18; Integrin beta chain; beta 2; LCAMB; MAC-1; MFI7; MF17; Integrin beta-2; LAD; LFA-1; Human ITGB2; MAC-1; CD18], [MAC-1; CD18] |
Gene, Accession # | [ITGB2], Gene ID: 3689, NCBI: NP_000202.2, UniProt: P05107 |
Catalog # | MBS245100 |
Price | $530 |
Order / More Info | Human ITGB2 / MAC-1 / CD18 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |