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Antigenic Specificity | Human BAD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: peptide corresponding to 15 amino acids near the C-terminus of human Bad. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins, such as Bax, Bid, and Bik, form a growing subclass of the Bcl-2 family. Another such protein is the Bcl-2-antagonist of cell death (Bad). Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax. |
Immunogen | Immunogen Description: Synthetic peptide from human BAD. |
Other Names | [BAD (C-Terminus) IHC-plus; BAD; BBC2; Bcl-2-like protein 8; BCL2-binding component 6; BCL2L8; BBC6; BCL-X/BCL-2 binding protein; Bcl-2-binding component 6; Bcl2 antagonist of cell death; BCL2-binding protein; Bcl2-L-8; Human BAD], [BAD; BAD; BBC2; BCL2L8; BBC6; BCL2L8; BAD; Bcl2-L-8] |
Gene, Accession # | [BAD], Gene ID: 572, NCBI: NP_004313.1, UniProt: Q92934 |
Catalog # | MBS240470 |
Price | $660 |
Order / More Info | Human BAD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |