Edit |   |
---|---|
Antigenic Specificity | RBBP5 |
Clone | [1C9-1C9-H10] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. UniPort Summary Function: As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. |
Immunogen | Immunogen: Purified recombinant human RBBP5 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of RBBP5 and does not cross-react with related proteins. Sequence Similarities: Contains 6 WD repeats. |
Other Names | [RBBP 5; RBBP-5; RBBP5; RBBP5_HUMAN; RBQ 3; RBQ3; Retinoblastoma binding protein 5; Retinoblastoma binding protein RBQ3; Retinoblastoma binding protein5; Retinoblastoma-binding protein 5; Retinoblastoma-binding protein RBQ-3; SWD1; SWD1, Set1c WD40 repeat protein, homolog], [RBQ3; SWD1; RBBP5] |
Gene, Accession # | [RBBP5], Gene ID: 5929, NCBI: NP_001180201.1, UniProt: Q15291 |
Catalog # | MBS475202 |
Price | $335 |
Order / More Info | RBBP5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |