ARFGEF2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ARFGEF2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ARFGEF2 antibody detects endogenous levels of total ARFGEF2. Function: Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma membrane. Probably is involved in the exit of GABA(A) receptors from the endoplasmic reticulum. Involved in constitutive release of tum |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Membrane. Golgi Apparatus. Cytoplasm > Perinuclear Region. Golgi Apparatus > Trans-Golgi Network By similarity. Endosome By similarity. Cytoplasm > Cytoskeleton > Microtubule Organizing Center > Centrosome. Cell Projection > Dendrite By similarity. Cytoplasmic vesicle By similarity. Cell Junction > Synapse by similarity. Cytoplasm > Cytoskeleton by similarity. Note: Translocates from cytoplasm to membranes upon cAMP treatment. Loc |
| Other Names | [ADP ribosylation factor guanine nucleotide exchange factor 2 (brefeldin A inhibited); ADP ribosylation factor guanine nucleotide exchange factor 2; ARFGEF 2; ARFGEF2; ARFGEP2; BIG 2; BIG2; Brefeldin A inhibited 2; Brefeldin A inhibited GEP 2; Brefeldin A inhibited guanine nucleotide exchange protein 2; dJ1164I10.1; FLJ23723] |
| Gene, Accession # | [ARFGEF2], Gene ID: 10564, NCBI: NP_006411.2, UniProt: Q9Y6D5 |
| Catalog # | MBS9605313 |
| Price | $240, $280 |
| Order / More Info | ARFGEF2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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