GAPVD1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGAPVD1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against GAPVD1. It was validated on Western Blot and immunohistochemistryTarget Description: GAPVD1 acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking. It acts as a GEF for the Ras-related protein RAB31 by exchanging bound GDP for free GTP, leading to regulate LC2A4/GLUT4 trafficking. In the absence of insulin, it maintains RAB31 in an active state and promotes a futile cycle between LC2A4/GLUT4 storage vesicles and early endosomes, retaining LC2A4/GLUT4 inside the cells. Upon insulin stimulation, it is translocated to the plasma membra
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GAPVD1
Other Names[GTPase-activating protein and VPS9 domain-containing protein 1 isoform 4; GTPase-activating protein and VPS9 domain-containing protein 1; GTPase-activating protein and VPS9 domain-containing protein 1; GTPase activating protein and VPS9 domains 1; GAPex-5; Rab5-activating protein 6]
Gene, Accession #[GAPVD1], Gene ID: 26130, NCBI: NP_056450, UniProt: Q14C86
Catalog #MBS3206384
Price$335
Order / More InfoGAPVD1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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