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Antigenic Specificity | GAPVD1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against GAPVD1. It was validated on Western Blot and immunohistochemistryTarget Description: GAPVD1 acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking. It acts as a GEF for the Ras-related protein RAB31 by exchanging bound GDP for free GTP, leading to regulate LC2A4/GLUT4 trafficking. In the absence of insulin, it maintains RAB31 in an active state and promotes a futile cycle between LC2A4/GLUT4 storage vesicles and early endosomes, retaining LC2A4/GLUT4 inside the cells. Upon insulin stimulation, it is translocated to the plasma membra |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GAPVD1 |
Other Names | [GTPase-activating protein and VPS9 domain-containing protein 1 isoform 4; GTPase-activating protein and VPS9 domain-containing protein 1; GTPase-activating protein and VPS9 domain-containing protein 1; GTPase activating protein and VPS9 domains 1; GAPex-5; Rab5-activating protein 6] |
Gene, Accession # | [GAPVD1], Gene ID: 26130, NCBI: NP_056450, UniProt: Q14C86 |
Catalog # | MBS3206384 |
Price | $335 |
Order / More Info | GAPVD1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |