AKT (Phospho Thr308) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT (Phospho Thr308)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-Akt (T308) Polyclonal Antibody detects endogenous levels of Akt protein only when phosphorylated at T308. The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threon
ImmunogenImmunogen: Synthesized peptide derived from human Akt around the phosphorylation site of T308
Other Names[Rabbit Akt (phospho Thr308); AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B]
Gene, Accession #[AKT], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749
Catalog #MBS9701020
Price$130, $220, $325
Order / More InfoAKT (Phospho Thr308) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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