Edit |   |
---|---|
Antigenic Specificity | Human SCF |
Clone | [13F4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Mature human SCF consists of a 189 amino acid (aa) extracellular domain (ECD), a 23 aa transmembrane segment, and a 36 aa cytoplasmic tail. The ECD shows both N-linked and O-linked glycosylation. Proteolytic cleavage at two alternate sites in the extracellular juxtamembrane region releases a 25 kDa soluble molec |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with recombinant human SCF. |
Other Names | [KITLG; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7; kit-ligand], [KITLG; KITLG; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7; MGF; SCF; MGF; SCF; sKITLG] |
Gene, Accession # | [SCF], Gene ID: 4254, NCBI: NP_000890.1, UniProt: P21583 |
Catalog # | MBS690638 |
Price | $490 |
Order / More Info | Human SCF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |