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Antigenic Specificity | CD71 / Transferrin Receptor (TFRC) |
Clone | [TFRC/1149] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. |
Immunogen | Immunogen: Recombinant human TFRC protein |
Other Names | [Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR], [TFRC; TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46; TR; TfR; TfR1; Trfr; sTfR] |
Gene, Accession # | [TFRC], Gene ID: 7037, NCBI: NP_001121620.1, UniProt: P02786 |
Catalog # | MBS439109 |
Price | $190, $340, $340 |
Order / More Info | CD71 / Transferrin Receptor (TFRC) Antibody from MYBIOSOURCE INC. |
Product Specific References | Van de Rijna M, Geurts van Kessel AHM, Kroezen V, van Agthoven AJ, Verstijnen K, Terhorst C, Hilgers J: Cytogenet Cell Genet 1983;36:525-531. Oudermans et al. Cancer, 1986; 58:1252. K. Moolenaar et al. Cancer research 50,1102-1106, 1990 |