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Antigenic Specificity | APS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: APS Polyclonal Antibody detects endogenous levels of APS protein. The SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human APS |
Other Names | [Rabbit APS; SH2B2; APS; SH2B adapter protein 2; Adapter protein with pleckstrin homology and Src homology 2 domains; SH2 and PH domain-containing adapter protein APS] |
Gene, Accession # | [APS], Gene ID: 10603, NCBI: NP_066189.3, UniProt: O14492 |
Catalog # | MBS9704162 |
Price | $130, $220, $325 |
Order / More Info | APS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |