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Antigenic Specificity | CD38 [HB7] |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody binds to an epitope between amino acids 273-285 of human CD38, an approximately 45 kDa type II transmembrane protein, expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. Also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Bimodally expressed during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. This antibody competes with clone AT13/5 (Ab00289) (Ellis 1995). Recombinant monoclonal antibody to CD38. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma HB7. This chimeric rabbit antibody was made using the variable domain sequen |
Immunogen | Immunogen: Viable cells (1 x 10E7) of the human cell line, BJAB (Human Burkitt lymphoma B cell line), which was were injected intraperitoneally into 8-week-old BALB/c mice. Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
Other Names | [ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; EC 3.2.2.5; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD38; p45; NAD(+) nucleosidase], [CD38; CD38; ADPRC1; ADPRC 1; ADPRC 1; cADPr hydrolase 1] |
Gene, Accession # | [CD38], Gene ID: 952, UniProt: P28907 |
Catalog # | MBS488084 |
Price | $425 |
Order / More Info | CD38 [HB7] Antibody from MYBIOSOURCE INC. |
Product Specific References | Tedder TF, Clement LT, Cooper MD. Discontinuous expression of a membrane antigen (HB-7) during B lymphocyte differentiation. Tissue Antigens. 1984 Sep; 24(3):140-9. PMID:6440308 |