HDAC1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HDAC1 |
| Clone | [1061CT1.3.1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM,kappa |
| Format | unconjugated |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Purified His-tagged HDAC1 protein was used to produced this monoclonal antibody. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitate |
| Immunogen | n/a |
| Other Names | [Histone deacetylase 1; HD1; HDAC1; RPD3L1] |
| Gene, Accession # | [HDAC1], Gene ID: 3065, NCBI: NP_004955.2, UniProt: Q13547 |
| Catalog # | MBS9200432 |
| Price | $165, $370 |
| Order / More Info | HDAC1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Taunton J., et al. Science 272:408-411(1996). Furukawa Y., et al. Cytogenet. Cell Genet. 73:130-133(1996). Sparrow D.B., et al. EMBO J. 18:5085-5098(1999). Huynh K.D., et al. Genes Dev. 14:1810-1823(2000). Cai R.L., et al. J. Biol. Chem. 275:27909-27916(2000). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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