Phospho-HER4-Y1284 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-HER4-Y1284
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe HER/ErbB receptor tyrosine kinase family has been implicated in normal development, cardiac function and cancer (1,2). HER4/ErbB4, like other family members, has four ectodomains, a single transmembrane domain and a cytoplasmic tail containing the active tyrosine kinase domain (3). By binding to neuregulins and/or EGF family ligands, ErbB4 forms either a homodimer or heterodimer with other ErbB family members, which results in receptor activation and signaling (3). ErbB4 is ubiquitously expressed with the highest expression occurring in brain and heart. The expression of ErbB4 in breast cancer, pediatric brain cancer and other types of carcinomas has been reported suggesting that ErbB4 expression is involved in both normal tissue develo
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding Y1284 of human HER4
Other Names[Phospho-ERBB4-Y1284: ERBB4; HER4; p180erbB4; MGC138404], [ERBB4; ERBB4; HER4; ALS19; p180erbB4; HER4; 4ICD; E4ICD]
Gene, Accession #[ErbB4], Gene ID: 2066, NCBI: Q15303.1, UniProt: Q15303
Catalog #MBS125808
Price$235, $350, $525
Order / More InfoPhospho-HER4-Y1284 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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