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Antigenic Specificity | ATF7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ATF7 protein. Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ATF7. |
Other Names | [ATFA; activating transcription factor 7; cyclic AMP-dependent transcription factor ATF-7] |
Gene, Accession # | [ATF7], Gene ID: 11016, NCBI: NP_001123532.1, UniProt: P17544 |
Catalog # | MBS9408837 |
Price | $200, $255 |
Order / More Info | ATF7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |