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Antigenic Specificity | ENAH/MENA (Actin Regulator) |
Clone | [ENAH/1988] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2c, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance. |
Immunogen | Immunogen: Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary) |
Other Names | [ENA; ENAH; MENA; NDPP1] |
Gene, Accession # | [ENAH], Gene ID: 55740, NCBI: AAH65238.1, UniProt: Q8N8S7 |
Catalog # | MBS4381196 |
Price | $190, $340, $340 |
Order / More Info | ENAH/MENA (Actin Regulator) Antibody from MYBIOSOURCE INC. |
Product Specific References | Stewart, D.M., et al. 1996. J. Clin. Invest. 97: 2627-2634. |