Human SATB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman SATB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatDyLight 488 conjugate
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionSpecificity: No cross reactivity with other proteins. SATB1 (special AT-rich sequence-binding protein-1) is a protein which in humans is encoded by the SATB1 gene. SATB1, the global chromatin organizer and transcription factor, has emerged as a key factor integrating higher-order chromatin architecture with gene regulation. Recent studies have unraveled the role of SATB1 in organization of chromatin 'loopscape' and its dynamic nature in response to physiological stimuli. At genome-wide level, SATB1 seems to play a role in organization of the transcriptionally poised chromatin. SATB1 organizes the MHC class-I locus into distinct chromatin loops by tethering MARs to nuclear matrix at fixed distances. Silencing of SATB1 mimics the effects of I
ImmunogenImmunogen: E Coli-derived human SATB1 recombinant protein (Position: D638-D763).
Other Names[Rabbit IgG Human SATB1 DyLight 488 Conjugated, Flow Validated; DNA-binding protein SATB1; Special AT-rich sequence-binding protein 1; SATB1; SATB homeobox 1]
Gene, Accession #[SATB1], Gene ID: 6304, NCBI: NP_001124482.1, UniProt: Q01826
Catalog #MBS1751330
Price$330
Order / More InfoHuman SATB1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Galande S, Purbey PK, Notani D, Kumar PP (Oct 2007). The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1. Current Opinion in Genetics & Development. 17 (5): 408-14. 2. Pavan Kumar P, Purbey PK, Sinha CK, Notani D, Limaye A, Jayani RS, Galande S (Apr 2006). Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. Molecular Cell. 22 (2): 231-43.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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