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Antigenic Specificity | FAK2 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.6 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Protein-tyrosine kinase 2-beta / Focal adhesion Kinase 2 Antibody. Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and a |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 700-750 on human focal adhesion kinase 2 protein. Immunoglobulin: IgY. Expression: Most abundant in the brain, with highest levels in amygdala and hippocampus. Low levels in kidney (at protein level). Also expressed in spleen and lymphocytes. |
Other Names | [CADTK; CAK beta; CAKB; Calcium dependent tyrosine kinase; Calcium regulated non receptor proline rich tyrosine kinase; Cell adhesion kinase beta; E430023O05Rik; EC 2.7.10.2; FADK2; FAK2; Focal Adhesion Kinase 2; MGC124628; PKB; pp125FAK; Proline Rich Tyrosine Kinase 2; Protein kinase B; Protein Tyrosine Kinase 2 Beta; PTK; PTK2B protein tyrosine kinase 2 beta; PYK 2; RAFTK; RAFTK2; Related adhesion focal tyrosine kinase], [PTK2B; PTK2B; PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK; FAK2; PYK2; RAFTK; CADTK; CAK-beta; CAKB; FADK 2; RAFTK] |
Gene, Accession # | [FAK2], Gene ID: 2185, NCBI: Q14289.2, UniProt: Q14289 |
Catalog # | MBS541571 |
Price | $390 |
Order / More Info | FAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |