FAK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAK2
Clonepolyclonal
Host SpeciesChicken
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.6 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionAffinity Purified Protein-tyrosine kinase 2-beta / Focal adhesion Kinase 2 Antibody. Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and a
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 700-750 on human focal adhesion kinase 2 protein. Immunoglobulin: IgY. Expression: Most abundant in the brain, with highest levels in amygdala and hippocampus. Low levels in kidney (at protein level). Also expressed in spleen and lymphocytes.
Other Names[CADTK; CAK beta; CAKB; Calcium dependent tyrosine kinase; Calcium regulated non receptor proline rich tyrosine kinase; Cell adhesion kinase beta; E430023O05Rik; EC 2.7.10.2; FADK2; FAK2; Focal Adhesion Kinase 2; MGC124628; PKB; pp125FAK; Proline Rich Tyrosine Kinase 2; Protein kinase B; Protein Tyrosine Kinase 2 Beta; PTK; PTK2B protein tyrosine kinase 2 beta; PYK 2; RAFTK; RAFTK2; Related adhesion focal tyrosine kinase], [PTK2B; PTK2B; PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK; FAK2; PYK2; RAFTK; CADTK; CAK-beta; CAKB; FADK 2; RAFTK]
Gene, Accession #[FAK2], Gene ID: 2185, NCBI: Q14289.2, UniProt: Q14289
Catalog #MBS541571
Price$390
Order / More InfoFAK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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