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Antigenic Specificity | Mouse CD49d |
Clone | [PS/2] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2b |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | IgG concentration 0.1 mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Mouse CD49d monoclonal antibody, clone PS/2 recognizes murine alpha 4 integrin (CD49d), a ~150kDa single pass type I membrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively (Holzmann et al. 1989). CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1 (Sheppard et al. 1994). Clone PS/2 has also been reported to block the binding of CD49d to its ligands (Andrew et al. 1994). |
Immunogen | n/a |
Other Names | [integrin alpha-4; Integrin alpha-4; integrin alpha-4; CD49 antigen-like family member D; LPAM subunit alpha; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha; integrin alpha-IV; integrin alpha4B; lymphocyte Peyer patch adhesion molecules subunit alpha; integrin alpha 4; CD49 antigen-like family member D; Integrin alpha-IV; Lymphocyte Peyer patch adhesion molecules subunit alpha; LPAM subunit alpha; VLA-4 subunit alpha; CD_antigen: CD49d], [Itga4; Itga4; CD49D; Itga4B; LPAM subunit alpha] |
Gene, Accession # | [CD49d], Gene ID: 16401, NCBI: NP_034706.3, UniProt: Q00651 |
Catalog # | MBS210637 |
Price | $370 |
Order / More Info | Mouse CD49d Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |