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Antigenic Specificity | Sodium-Iodide Symporter |
Clone | [FP5] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 kappa |
Format | PE-ATTO 594 conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Mapped to AA 625-643 of hNIS. Apparent mol. wt of 97kD,non-glycosylated version at 68kD. Other minor bands associated with hNIS at160kDa, and degradation products at ~30 kDa, and ~15kDa. Scientific Background: The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3). |
Immunogen | n/a |
Other Names | [NIS; SLC5A5; solute carrier family 5; Na (+)I(-) cotransporter], [SLC5A5; SLC5A5; NIS; TDH1; NIS; Na(+)/I(-) cotransporter; Na(+)/I(-) symporter] |
Gene, Accession # | Gene ID: 6528, NCBI: NP_000444.1, UniProt: Q92911 |
Catalog # | MBS800546 |
Price | $445 |
Order / More Info | Sodium-Iodide Symporter Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Dai G., Levy O., Carrasco N. (1996) Nature. 379(6564): 458-460. 2. Snabik P.A., et al. (1997) Endocrin. 138(8): 3555-3558. 3. Dohan O., et al. (2007) Proc Natl Acad Sci USA. 104(51): 20250-20255. |