LGR6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLGR6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
ImmunogenImmunogen: Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 6 protein (839-962AA)
Other Names[Leucine-rich repeat-containing G-protein coupled receptor 6; LGR6; ORF Names:UNQ6427/PRO21331; VTS20631]
Gene, Accession #[LGR6], Gene ID: 59352, NCBI: NP_001017403.1, UniProt: Q9HBX8
Catalog #MBS7105429
Price$160, $235
Order / More InfoLGR6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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